Metformin

Treats the insulin resistance behind PCOS (when your body doesn't respond well to insulin). Dosed to your blood work.

$0 until a clinician approves · FSA/HSA eligible

$0 until a clinician approves.

Clinician-reviewed in 24 hours
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To get a prescription, you need an online visit reviewed by a U.S.-licensed provider. Compounded medicines are made by licensed U.S. pharmacies and are not FDA-approved. Results vary from person to person.

Who it’s for

Perimenopause or menopause symptoms (sleep, hot flashes, mood)
PCOS, irregular cycles, or hormonal acne
Want a clinician who checks your labs before prescribing

See if I qualify

PCOS and insulin resistance often go together. Metformin works on that part.

What the first months look like

Before day 1

Blood work comes first. Your clinician checks things like blood sugar and kidney function before deciding whether metformin is right for you.

First weeks

Getting used to it. Stomach upset is the most common early side effect. Starting low and taking it with food usually helps it settle.

Early months

Changes come slowly. Some people see changes in their cycle or weight over several months. Others don't. Patience is part of the plan.

Ongoing

Check-ins and repeat labs as your clinician advises. Your dose is adjusted based on how you respond and how well you tolerate it.

Dosing, step by step

Metformin	Set by your clinician, raised slowly — starting low and taking it with food helps keep stomach side effects small

Your clinician sets your dose and raises it slowly. Staying on a dose or stepping down is normal.

And when it gets rough

Show what helps

Stomach upset, early on Take it with food, and let the slow dose increase do its job. If the trouble doesn't go away, talk to your clinician about your dose. Don't just push through.
Feeling unwell in a way that worries you Contact your clinician the same day. If you feel very sick, have trouble breathing, or have severe stomach pain, get emergency care.

Why we start you here

Metformin may help some people with PCOS. This use is off-label, which means PCOS isn't what it was approved for. We check your metabolic health and kidney function before prescribing. Stomach side effects can happen, and ones that don't go away need a check. Taking it for a long time can lower vitamin B12. Your plan is set for you, and more regular periods aren't guaranteed. Acne or extra hair growth may need a different treatment.

Medical Director · Zappy clinical team

How it works

Three steps, no insurance hoops

Take the quiz

About 5 minutes. Tell us your symptoms, history, and goals.

Clinician reviews

A U.S.-licensed clinician looks at your answers within 24 hours. If it's right for you, they write your plan.

Care ships free

Your medication arrives in days. Refills come on their own, and check-ins are included.

Common questions

How much does Metformin cost?

From $63/mo on a 6‑month plan, or $79 if you pay month to month. That price covers everything: the medication and your clinician's care. There's no membership fee, and the price is the same at every dose. You'll see the full price before checkout. You pay nothing unless a clinician approves you.

Is Metformin FDA-approved?

No. Compounded medicines are made for you by licensed U.S. pharmacies, based on your prescription. They are not FDA-approved.