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Read a long guide when you want the full picture. Read a short answer when you have one question. Articles are reviewed and dated by our clinical team, led by our medical director.
17 guides · 60 answers · 5 care areas
Weight loss
GLP-1 medicine that turns down food noise.
A GLP-1 grocery list: what to buy and what to skip
An aisle-by-aisle grocery list for semaglutide or tirzepatide, with USDA protein counts, cheaper ways to buy protein, what to leave on the shelf, and a one-week list for one person.
How sleep affects weight loss on a GLP-1
Short sleep raises hunger hormones and, in one controlled study, shifted weight loss away from fat and toward lean mass. Why semaglutide and tirzepatide can disrupt sleep, and an evening routine that targets those causes.
Do weight loss supplements work?
A few supplements have trial evidence for weight loss, and the best of them average less than a kilogram over placebo. Which ones those are, which are marketing, how to buy safely, and which make sense alongside a GLP-1.
Emotional eating, after GLP-1
A GLP-1 turns down hunger, but it doesn't remove the other reasons you eat. How to name your pattern, and why the time you spend on the drug matters.
Alcohol on a GLP-1
You can drink, since alcohol and semaglutide don't directly interact. But drinks hit harder on a slow stomach, use up a tight calorie budget, and some people want alcohol less anyway.
Can GLP-1s affect your mood?
In January 2026 the FDA took the suicidal-thoughts warning off the Wegovy and Zepbound labels. Here is what can lower mood early on, what helps, and when to get help the same day.
Compounded semaglutide cost, itemized
At Zappy you pay one flat monthly price that covers your clinician visit, the medication, and shipping. Here's what that buys, what it doesn't (FDA approval), and how it compares to the brand-name pen.
Peptides & longevity
NAD+, glutathione, and sermorelin, with a clinician involved. Evidence for energy, recovery, or aging benefits is limited.
How peptides work: the practical guide
Some peptides have large trials behind them. Others are sold on a diagram alone. Here's what the evidence supports, and where it runs out.
Fatigue on GLP-1: what to check, and where NAD+ fits
Tiredness on a GLP-1 has many possible causes, from eating less to poor sleep. Here's what your clinician checks, and why NAD+ isn't a proven fix.
How long should a peptide cycle be?
There's no standard peptide cycle. GLP-1 medicines are meant for long-term use. For sermorelin and NAD+, the evidence on how long to take them is thin. Here's what we know.
NAD+ and GLP-1: should you add NAD+?
The GLP-1 does the weight loss. Adding NAD+ for tiredness has no trial behind it. Here's how we look at fatigue first, and what proof would change our view.
Women's health
Bioidentical HRT, PCOS care, and cycle support, planned around your symptoms and health history.
GLP-1 and PCOS: why these medications work
Most PCOS is driven by insulin resistance, and GLP-1s lower it. Here's how they work, and where the PCOS evidence stands.
GLP-1, birth control, and PCOS: what changes
GLP-1s can restart ovulation before your cycle looks regular. Two birth control details decide your method. Here's how to choose.
Hot flash relief: the options ranked
For most women who can take it, estrogen works better than any non-hormone option. Here's the full ranking: risks, backups, add-ons, and what's just marketing.
Men's health
Testosterone, hair loss, and ED care, starting with the right tests.
A weight loss diet that actually works for men
On a GLP-1, the medicine cuts the calories. Your job with food is protein, so the weight you lose doesn't come off your muscle.
Can testosterone make you gain weight?
In men with truly low levels, treatment tends to shift muscle and fat more than the scale. Testosterone isn't a weight-loss drug. If fat loss is your goal, it's the wrong tool.
Erectile dysfunction and weight loss
ED is often a blood-flow problem, and extra weight makes it worse. Here's how weight loss may help, what we know, and how we plan care.
Hair & skin
Prescription skincare, compounded for your skin and prescribed by U.S.-licensed clinicians.
Anti-aging skincare: what actually works
Two things carry the evidence: daily sunscreen and a nightly retinoid. Everything else makes only a small difference. Build a routine in five minutes, not fifty.
Botox vs fillers: when to use which
Botox relaxes muscle. Fillers replace lost volume. To tell which you need, check if the line shows up when you move or stays when your face is still.
Can poor diet cause hair loss? Yes, and here's how
Your body treats hair as optional. Eat too little and it cuts hair first. Why fast GLP-1 weight loss can trigger it, and the nutrients worth checking.
GLP-1 and dull skin: what glutathione does (and doesn't)
Skin can look duller during fast GLP-1 weight loss. Here's what to check first, and why glutathione isn't a proven fix.