Peptides & longevity

NAD+

NAD+ (nicotinamide adenine dinucleotide) is a helper molecule your cells use. This is NAD+ given as a shot, with a clinician overseeing your care. The evidence for energy, recovery, or aging benefits is still limited.

See if I qualifyFrom $143/mo

$0 until a clinician approves · FSA/HSA eligible

$0 until a clinician approves.

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To get a prescription, you need an online visit reviewed by a U.S.-licensed provider. Compounded medicines are made by licensed U.S. pharmacies and are not FDA-approved. Results vary from person to person.

Who it’s for

Want an honest talk about what these treatments can and can't do
Want a clinician involved, instead of gray-market vials
OK with small shots under the skin (most courses)

See if I qualify

Being tired all the time is worth a proper check before any new treatment.

How it works

NAD+ is a coenzyme (a helper molecule) your cells need to make energy and repair DNA. You can take it as a shot, a nasal spray, or oral precursors.

Read the full NAD+ profile →

What we can and can't tell you

Your body needs NAD+, but that doesn't prove NAD+ shots improve energy, recovery, or aging. The evidence for those uses is still limited. Most human research is on oral precursors (pills your body turns into NAD+), and raising a level is not the same as a health benefit. We don't promise results.

Who makes it A LegitScript-verified 503A compounding pharmacy makes it from your prescription. We never use gray-market or overseas suppliers.
To what standard USP <797> standards for sterile compounding, and USP <800> standards for handling hazardous drugs, where they apply

How we source and ship →

Compounded medicines are not FDA-approved. The FDA does not review them for safety or effectiveness. They are not generic versions of any brand-name drug, and they are not equivalent to one.

What the first months look like

First sessions

Your clinician starts at a low dose. Tell them about any reaction, like flushing, headache, or nausea. A reaction deserves a check. Don't assume it's only the dose or the speed.

Early weeks

Any change in how you feel varies from person to person, and it doesn't prove the treatment works. Benefits have not been proven.

Ongoing

If you and your clinician decide to continue, you follow the schedule they set. Continuing is a decision, not a default.

Check-ins

Your clinician checks how you're handling it and reviews your dose. Report any reaction so it can be assessed.

Dosing, step by step

Injection	100–500 mg subcutaneous — 1–3× a week, with a clinician overseeing it
Nasal spray	50–100 mg daily — used on and off

These ranges come from the ingredient profile. Your clinician sets your actual dose and schedule, and adjusts for how you handle it.

And when it gets rough

Show what helps

Flushing Tell your clinician so they can assess it. Get urgent care for trouble breathing, swelling of the face or throat, chest pain, or fainting.
Headache Tell your clinician, especially if it's strong or doesn't go away. They'll look at the cause.
Nausea Tell your clinician. They'll assess it instead of assuming it's just the dose.
Injection-site reactions Use a different spot each time. Mild redness where you inject is common and goes away soon. Contact your clinician if a reaction spreads or won't go away.

Full safety profile →

Safety information

A U.S.-licensed clinician reviews every prescription and decides whether this medicine is right for you. During your visit, tell them if any of the following applies to you or your family.

Common side effects

Flushing, Headache, Nausea (more likely at higher doses)

Less common

Reactions where you inject

Interactions

Generally few. Check with your clinician if you take metformin

Full safety profile → See if I qualify

Why we start you here

Your body needs NAD+, but that doesn't prove NAD+ shots improve energy, recovery, or aging. The evidence for those uses is still limited. Reactions shouldn't be brushed off as just a dose or speed problem. The FDA has reported serious reactions to injectable NAD+ products, including some that matched contamination. If you're tired all the time, get that checked before trying an unproven treatment.

Medical Director · Zappy clinical team

How it works

Three steps, no insurance hoops

Take the quiz

About 5 minutes. Tell us your symptoms, history, and goals.

Clinician reviews

A U.S.-licensed clinician looks at your answers within 24 hours. If it's right for you, they write your plan.

Care ships free

Your medication arrives in days. Refills come on their own, and check-ins are included.

Comparing options?

NAD: injection vs spray →

Common questions

How much does NAD+ cost?

From $143/mo on a 6‑month plan, or $179 if you pay month to month. That price covers everything: the medication and your clinician's care. There's no membership fee, and the price is the same at every dose. You'll see the full price before checkout. You pay nothing unless a clinician approves you.

How is NAD+ taken?

Shot: 100–500 mg under the skin, 1–3× a week, with a clinician supervising. Nasal spray: 50–100 mg daily, on and off.

What are the side effects of NAD+?

Common: flushing, headache, nausea (more likely at higher doses). Less common: reactions where you inject. Your clinician checks your health history before prescribing. They'll change your plan if side effects come up.

Does NAD+ interact with other medications?

Tell your clinician about everything you take. Known interactions: Generally few. Check with your clinician if you take metformin.

Is NAD+ FDA-approved?

No. Compounded medicines are made for you by licensed U.S. pharmacies, based on your prescription. They are not FDA-approved.